With a psychopath named Buffalo Bill murdering women and believing it takes one to know one, the FBI sends Agent Clarice Starling (Jodie Foster) to interview a demented prisoner: Dr. Hannibal Lecter (Anthony Hopkins), a cannibalistic psychiatrist whose fascination with the young agent is as great as his hunger for murder. As their relationship develops, Starling is forced to confront not only her own demons, but also an evil so powerful she may not have the courage to stop!